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Article

Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification.

Circulation research - 9 May 2008

Elsherif Laila, Huang Michael S, Shai Shaw-Yung, Yang Yuan, Li Rita Y, Chun June, Mekany Majid A, Chu Andrew L, Kaufman Stephen J, Ross Robert S

Abstract excerpt

The dystrophin-glycoprotein complex is a large complex of membrane-associated proteins linking the cytoskeleton to the extracellular matrix in muscle. Transmembrane heterodimeric (alphabeta) integrins serve also as cellular adhesion molecules and mechanotransducers. In the animal model for Duchen...

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Source

Identifiers

PMID: 18340010
DOI: 10.1161/CIRCRESAHA.108.173153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18340010-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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