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Article

Comparison of the effects of genistein and zoledronic acid on the bone loss in OPG-deficient mice.

Bone - 1 May 2008

Liu Jianghua, Xu Kang, Wen Gebo, Guo Hui, Li San, Wu Xianping, Dai Ruchun, Sheng Zhifeng, Liao Eryuan

Abstract excerpt

UNLABELLED: Using osteoprotegerin (OPG)-knockout mice, we demonstrated that in vivo the effects of both genistein and 17beta-estradiol (E2) on bone metabolism were completely abolished. In contrast, zoledronic acid could effectively suppress bone resorption and prevent bone loss. INTRODUCTION: Th...

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Identifiers

PMID: 18337202
DOI: 10.1016/j.bone.2008.01.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18337202-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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