Article
Haplotype-tagging single nucleotide polymorphisms in the GSTP1 gene promoter and susceptibility to lung cancer.
Cancer detection and prevention - 1 Jan 2009
Tan Xiang-Lin, Moslehi Roxana, Han WeiGuo, Spivack Simon D
Abstract excerpt
BACKGROUND: Glutathione S-transferase (GST) P1 is a major phase II xenobiotic-metabolizing enzyme in the human lung. Our laboratory had previously identified nine single nucleotide polymorphisms (SNPs) in the GSTP1 gene promoter, which were then grouped into three main haplotypes (Hap1, Hap2, and...
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