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Article

Interferon gamma allelic variants: sex-biased multiple sclerosis susceptibility and gene expression.

Archives of neurology - 1 Mar 2008

Kantarci Orhun H, Hebrink David D, Schaefer-Klein Janet, Sun Yulong, Achenbach Sara, Atkinson Elizabeth J, Heggarty Shirley, Cotleur Anne C, de Andrade Mariza, Vandenbroeck Koen, Pelfrey Clara M, Weinshenker Brian G

Abstract excerpt

BACKGROUND: Interferon (IFN) gamma (IFNG) allelic variants are associated with susceptibility to multiple sclerosis (MS) in men but not in women. OBJECTIVES: To conduct a high-density linkage disequilibrium association study of IFNG and the surrounding region for sex-associated MS susceptibility bias and to evaluate whether IFNG allelic variants associated with MS susceptibility are associated with expression....

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Identifiers

PMID: 18332247
DOI: 10.1001/archneurol.2007.66

Genes

IFNG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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