Pharmacogenomics of response to interferon-beta and glatiramer acetate in Multiple Sclerosis: A multi-centric study.

doi:10.1177/13524585261417130

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Pharmacogenomics of response to interferon-beta and glatiramer acetate in Multiple Sclerosis: A multi-centric study.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jun 2026

Corona Andrea, Clarelli Ferdinando, Pääkkönen Kimmo, Harroud Adil, Shchetynsky Klementy, Zollo Alen, Mingione Alessandra, Sorosina Melissa, Mascia Elisabetta, Giordano Antonino, Rocca Maria Assunta, Piehl Fredrik, Stridh Pernilla, Hemmer Bernhard, Goris An, Dubois Bénédicte, Søndergaard Helle Bach, Sellebjerg Finn, D'alfonso Sandra, Harbo Hanne Flinstad, Olsson Tomas, Saarela Janna, Priori Alberto, Filippi Massimo, Kockum Ingrid, Esposito Federica, Martinelli Boneschi Filippo

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) treatment response varies significantly, hindering effective management and necessitating better predictive biomarkers. Pharmacogenomics offers a promising avenue to identify genetic markers that, combined with clinico-demographic predictors, could enhance personalized therapeutic decisions. OBJECTIVES: This multi-center study investigated genetic determinants of response to...

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PMID: 41776383
DOI: 10.1177/13524585261417130

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ZCCHC7
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