Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the genes encoding interferon-gamma and interferon-gamma receptors in multiple sclerosis.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 2004

Schrijver H M, Hooper-van Veen T, van Belzen M J, Crusius J B A, Peña A S, Barkhof F, Polman C H, Uitdehaag B M J

Abstract excerpt

Genome screens suggest that several genes, each contributing to a small extent, are involved in multiple sclerosis (MS) susceptibility. Simultaneous analysis of related genes may improve the power to detect such small effects. Interferon-gamma (IFN-gamma), mediating its effects through the IFN-gamma receptor, is a pleiotropic, pro-inflammatory cytokine for which a detrimental effect on the course of MS has been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-gamma

Share to Interferon gamma Receptor

Share to Magnetic Resonance Imaging

Share to Multiple Sclerosis

Share to Netherlands

Share to Receptors, Interferon

Source

Identifiers

PMID: 15182327
DOI: 10.1111/j.1365-2370.2004.00456.x

Genes

IFNGR2
IFNG
IFNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the genes encoding interferon-gamma and interferon-gamma receptors in multiple sclerosis.PMID 15182327Read ↗

Interferon gamma allelic variants: sex-biased multiple sclerosis susceptibility and gene expression.Semantic proximity Read ↗

Analysis of an interferon-gamma gene dinucleotide-repeat polymorphism in Nordic multiple sclerosis patients.Semantic proximity Read ↗

IFNG polymorphisms are associated with gender differences in susceptibility to multiple sclerosis.Semantic proximity Read ↗

IL-2, IFN-gamma, and IL-12 gene polymorphisms and susceptibility to multiple sclerosis.Semantic proximity Read ↗

Single nucleotide polymorphisms in multiple sclerosis: disease susceptibility and treatment response biomarkers.Semantic proximity Read ↗

Pharmacogenomic analysis of interferon receptor polymorphisms in multiple sclerosisSemantic proximity Read ↗

Single-nucleotide polymorphisms in response to interferon-beta therapy in multiple sclerosis.Semantic proximity Read ↗

Pharmacogenetics of multiple sclerosisSemantic proximity Read ↗

IFN-beta pharmacogenomics in multiple sclerosis.Semantic proximity Read ↗

IFNAR1 and IFNAR2 polymorphisms confer susceptibility to multiple sclerosis but not to interferon-beta treatment response.Semantic proximity Read ↗

Multiple sclerosis and hepatitis C virus infection are associated with single nucleotide polymorphisms in interferon pathway genes.Semantic proximity Read ↗

Multiple sclerosis susceptibility loci do not alter clinical and MRI outcomes in clinically isolated syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.