Article
Implication of the Drosophila beta-amyloid peptide binding-like protein AMX in Notch signaling during early neurogenesis.
Brain research bulletin - 18 Mar 2008
Michellod Marie-Agnès, Randsholt Neel B
Abstract excerpt
Lateral inhibition provides a mechanism to regulate neuroblast specification during early neurogenesis in Drososphila melanogaster embryos. This mechanism is mediated by the highly conserved Notch pathway. Defective lateral inhibition results in CNS hyperplasia at the expense of ectoderm development, hence genes causing this defect are called neurogenic. D. melanogaster almondex (amx) is a maternal neurogenic...
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