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Article

Using disease symptoms to improve detection of linkage under genetic heterogeneity.

Genetic epidemiology - 1 Jul 2008

Bureau Alexandre, Labbe Aurélie, Croteau Jordie, Mérette Chantal

Abstract excerpt

A major reason for the slow progress in identifying susceptibility genes for complex diseases may be that the clinical diagnoses used as phenotypes are genetically heterogeneous. This has led researchers to collect various phenotypes related to the diagnosis, such as detailed symptoms, in the hop...

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PMID: 18330904
DOI: 10.1002/gepi.20320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18330904-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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