Article
Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk.
The American journal of clinical nutrition - 1 Mar 2008
Lee Sang-Ah, Fowke Jay H, Lu Wei, Ye Chuangzhong, Zheng Ying, Cai Qiuyin, Gu Kai, Gao Yu-Tang, Shu Xiao-ou, Zheng Wei
Abstract excerpt
BACKGROUND: Cruciferous vegetables are the primary source of isothiocyanates and other glucosinolate derivatives that are known to induce phase II detoxifying enzymes, including glutathione S-transferases (GSTs). OBJECTIVE: We investigated the independent and combined effects of cruciferous vegetable intake and the GSTP1 Ile(105)Val genetic polymorphism on breast cancer risk. DESIGN: Analyses included 3035 cases...
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