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Article

Potent antimycobacterial activity of mouse secretory leukocyte protease inhibitor.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2008

Nishimura Junichi, Saiga Hiroyuki, Sato Shintaro, Okuyama Megumi, Kayama Hisako, Kuwata Hirotaka, Matsumoto Sohkichi, Nishida Toshirou, Sawa Yoshiki, Akira Shizuo, Yoshikai Yasunobu, Yamamoto Masahiro, Takeda Kiyoshi

Abstract excerpt

Secretory leukocyte protease inhibitor (SLPI) has multiple functions, including inhibition of protease activity, microbial growth, and inflammatory responses. In this study, we demonstrate that mouse SLPI is critically involved in innate host defense against pulmonary mycobacterial infection. Dur...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18322212
DOI: 10.4049/jimmunol.180.6.4032

Genes

SLPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18322212-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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