Article
Expression and characterization of group A Streptococcus extracellular cysteine protease recombinant mutant proteins and documentation of seroconversion during human invasive disease episodes.
Infection and immunity - 1 Feb 1998
Gubba S, Low D E, Musser J M
Abstract excerpt
A recent study with isogenic strains constructed by recombinant DNA strategies unambiguously documented that a highly conserved extracellular cysteine protease expressed by Streptococcus pyogenes (group A Streptococcus [GAS]) is a critical virulence factor in a mouse model of invasive disease (S....
Topics
- Animals
- Bacterial Proteins
- Cysteine Endopeptidases
- Enzyme Precursors
- Humans
- Molecular Weight
- Mutation
- Rabbits
- Recombinant Proteins
- Streptococcal Infections
- Streptococcus pyogenes