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Article

Common variants within MECP2 confer risk of systemic lupus erythematosus.

PloS one - 5 Mar 2008

Sawalha Amr H, Webb Ryan, Han Shizhong, Kelly Jennifer A, Kaufman Kenneth M, Kimberly Robert P, Alarcón-Riquelme Marta E, James Judith A, Vyse Timothy J, Gilkeson Gary S, Choi Chan-Bum, Scofield R Hal, Bae Sang-Cheol, Nath Swapan K, Harley John B

Abstract excerpt

Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease that affects multiple organ systems. Herein, we report on an X-chromosome gene association with SLE. Methyl-CpG-binding protein 2 (MECP2) is located on chromosome Xq28 and encodes for a protein that plays a critical r...

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Identifiers

PMID: 18320046
DOI: 10.1371/journal.pone.0001727
PMCID: PMC2253825

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18320046-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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