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Article

The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.

PloS one - 5 Mar 2008

Ye Wenbin, Lv Qing, Wong Chung-Kwun Amy, Hu Sean, Fu Chao, Hua Zhong, Cai Guoping, Li Guoxi, Yang Burton B, Zhang Yaou

Abstract excerpt

MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent res...

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Identifiers

PMID: 18320040
DOI: 10.1371/journal.pone.0001719
PMCID: PMC2248708

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18320040-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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