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Article

Principles of miRNA-mRNA interactions: beyond sequence complementarity.

Cellular and molecular life sciences : CMLS - 1 Aug 2015

Afonso-Grunz Fabian, Müller Sören

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression by altering the translation efficiency and/or stability of targeted mRNAs. In vertebrates, more than 50% of all protein-coding RNAs are assumed to be subject to miRNA-mediated control, but current high-throughput methods that reliably measure miRNA-mRNA interactions either require prior knowledge of target mRNAs or...

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Identifiers

PMID: 26037721
DOI: 10.1007/s00018-015-1922-2
PMCID: PMC11114000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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