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Article

Essential tremor and the common LRRK2 G2385R variant.

Parkinsonism & related disorders - 1 Nov 2008

Tan Eng-King, Lee Jasinda, Lim Hui-Qin, Yuen Yih, Zhao Yi

Abstract excerpt

Co-existence of Parkinson's disease (PD) and essential tremor (ET) suggests a possible overlapping pathophysiology between these two conditions. PD patients with leucine-rich repeat kinase-2 (LRRK2) mutations have been reported to present initially with ET. A common LRRK2 Gly2385Arg variant has been widely shown to be associated with a two fold increased risk of PD in various Asian populations. We analyzed the...

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PMID: 18316234
DOI: 10.1016/j.parkreldis.2007.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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