Article
Two distinct structural elements of 5S rRNA are needed for its import into human mitochondria.
RNA (New York, N.Y.) - 1 Apr 2008
Smirnov Alexandre, Tarassov Ivan, Mager-Heckel Anne-Marie, Letzelter Michel, Martin Robert P, Krasheninnikov Igor A, Entelis Nina
Abstract excerpt
RNA import into mitochondria is a widespread phenomenon. Studied in details for yeast, protists, and plants, it still awaits thorough investigation for human cells, in which the nuclear DNA-encoded 5S rRNA is imported. Only the general requirements for this pathway have been described, whereas specific protein factors needed for 5S rRNA delivery into mitochondria and its structural determinants of import remain...
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