Article
tRNA mitochondrial import in yeast: Mapping of the import determinants in the carrier protein, the precursor of mitochondrial lysyl-tRNA synthetase.
Mitochondrion - 1 Apr 2010
Kamenski Piotr, Smirnova Ekaterina, Kolesnikova Olga, Krasheninnikov Igor A, Martin Robert P, Entelis Nina, Tarassov Ivan
Abstract excerpt
Mitochondria of many species import of nuclear DNA-encoded tRNAs. This widely spread but poorly studied phenomenon proved to be a promising tool for mitochondrial transfection. In yeast Saccharomyces cerevisiae, one cytosolic tRNAs(Lys) is partially targeted into mitochondria. Previous studies have shown that binding of this tRNA to its putative protein carrier, the precursor of mitochondrial lysyl-tRNA...
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