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Article

Secondary RNA structure and nucleotide specificity contribute to internal initiation mediated by the human tau 5' leader.

RNA biology - 1 Nov 2012

Veo Bethany L, Krushel Leslie A

Abstract excerpt

Mechanisms by which eukaryotic internal ribosomal entry sites (IRESs) initiate translation have not been well described. Viral IRESs utilize a combination of secondary/tertiary structure concomitant with sequence specific elements to initiate translation. Eukaryotic IRESs are proposed to utilize the same components, although it appears that short sequence specific elements are more common. In this report we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22995835
DOI: 10.4161/rna.22181
PMCID: PMC3597575

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