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Article

Serotonin transporter gene promoter (5-HTTLPR) and intron 2 (VNTR) polymorphisms in Croatian suicide victims.

Biological psychiatry - 1 Nov 2003

Hranilovic Dubravka, Stefulj Jasminka, Furac Ivana, Kubat Milovan, Balija Melita, Jernej Branimir

Abstract excerpt

BACKGROUND: Disturbances in serotonin (5HT) transmission are the most frequently reported neurobiological substrates of suicidal behavior. Because 5HT transporter plays a central role in the regulation of 5HT synaptic function and its gene contains two functional polymorphisms (5-HTTLPR in the promoter region and VNTR in the second intron), it represents an interesting candidate for association studies in...

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PMID: 14573315
DOI: 10.1016/s0006-3223(03)00179-3

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