Article
The frequency of drug resistance mutations in Mycobacterium leprae isolates in untreated and relapsed leprosy patients from Myanmar, Indonesia and the Philippines.
Leprosy review - 1 Dec 2007
Matsuoka Masanori, Budiawan Teky, Aye Khin Saw, Kyaw Kyaw, Tan Esterlina Virtudes, Cruz Eduardo Dela, Gelber Robert, Saunderson Paul, Balagon Victoria, Pannikar Vijaykumar
Abstract excerpt
INTRODUCTION: The magnitude of drug resistance in Mycobacterium leprae to dapsone, rifampicin, and ofloxacin was studied in three Southeast Asian countries with a high prevalence of leprosy. METHODS: M. leprae from the skin of leprosy patients was collected in North Maluku and North Sulawesi in Indonesia, Yangon in Myanmar, and Cebu in the Philippines. Mutations in the drug resistance determining regions in the...
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