Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered expression patterns of lipid metabolism genes in an animal model of HCV core-related, nonobese, modest hepatic steatosis

1 Jan 2008

Abstract excerpt

BACKGROUND: Because the gene expression patterns of nonobese hepatic steatosis in affected patients remain unclear, we sought to explore these patterns using an animal model of nonobese hepatic steatosis. METHODS: We developed mice that conditionally express the hepatitis C virus (HCV) core protein regulated by the tetracycline transactivator (tTA). Microarray analyses and reverse-transcription polymerase chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Hepatitis C virus research
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18307821
DOI: 10.1186/1471-2164-9-109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered expression patterns of lipid metabolism genes in an animal model of HCV core-related, nonobese, modest hepatic steatosisPMID 18307821Read ↗

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice.Semantic proximity Read ↗

The genetic architecture of NAFLD among inbred strains of miceSemantic proximity Read ↗

Liver specific transgenic expression of CYP7B1 attenuates early western diet-induced MASLD progressionSemantic proximity Read ↗

Hepatitis C virus core protein induces hepatic steatosis in transgenic mice.Semantic proximity Read ↗

Single-cell analysis of non-alcoholic fatty livers identifies a role for the constitutive androstane receptorSemantic proximity Read ↗

Metabolic alterations and hepatitis C: From bench to bedside.Semantic proximity Read ↗

Genetic determinants in hepatic fibrosis: from experimental models to fibrogenic gene signatures in humans.Semantic proximity Read ↗

The Genetic Architecture of Diet‐Induced Hepatic Fibrosis in MiceSemantic proximity Read ↗

Hepatic loss of AATF attenuates MASH by suppressing AKT–mTORC1 signaling and reprogramming lipid metabolismSemantic proximity Read ↗

Hepatic gene expression in patients with obesity‐related non‐alcoholic steatohepatitisSemantic proximity Read ↗

Hepatic Cholesteryl Ester Transfer Protein Regulates Sex-specific Liver Metabolic Adaptation and Metabolic-Associated Steatotic Liver Disease Risk in Diet-induced ObesitySemantic proximity Read ↗

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.