Article
Molecular mechanism of cholangiocarcinoma carcinogenesis.
Journal of hepato-biliary-pancreatic sciences - 1 Oct 2014
Maemura Kosei, Natsugoe Shoji, Takao Sonshin
Abstract excerpt
Cholangiocarcinoma (CCA) is a highly malignant cancer of the biliary tract with a poor prognosis, which often arises from conditions causing long-term inflammation, injury, and reparative biliary epithelial cell proliferation. Several conditions are known to be major risk factors for cancer in the biliary tract or gallbladder, including primary sclerosing cholangitis, liver fluke infection, pancreaticobiliary...
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