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STNM1 in human cancers: role, function and potential therapy sensitizer

16 Jun 2023

Abstract excerpt

STMN1 belongs to the stathmin gene family, it encodes a cytoplasmic phosphorylated protein, stathmin1, which is commonly observed in vertebrate cells. STMN1 is a structural microtubule-associated protein (MAP) that binds to microtubule protein dimers rather than microtubules, with each STMN1 binding two microtubule protein dimers and preventing their aggregation, leading to microtubule instability. STMN1...

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PMID: 37331415
DOI: 10.1016/j.cellsig.2023.110775

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