Article

Transcriptome analysis reveals vimentin-induced disruption of cell-cell associations augments cancer cell migration

2022-11-09

Abstract excerpt

<title>Abstract</title> <p>In advanced metastatic cancers with reduced patient survival and poor prognosis, expression of vimentin, a type III intermediate filament protein is frequently observed. Vimentin appears to suppress epithelial characteristics and augments cell migration but the molecular basis for these changes are not well understood. Here we have ectopically expressed vimentin in MCF-7 and investigate...

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Literature Corpus work: 337bccee-f66c-55bb-8bbc-b63067a341f6
DOI: 10.21203/rs.3.rs-2218271/v2

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