Article
Impact of population admixture on the distribution of the CYP3A5*3 polymorphism.
Pharmacogenomics - 1 Oct 2007
Suarez-Kurtz Guilherme, Perini Jamila A, Bastos-Rodrigues Luciana, Pena Sergio D J, Struchiner Cláudio
Abstract excerpt
OBJECTIVE: To compare the effectiveness of self-identified ethnic/color and marker-based biogeographical ancestry classifications in genotyping the CYP3A5*3 polymorphism in the Brazilian population. METHODS: Individual DNA from 308 healthy Brazilians, self-identified as white, intermediate and black was genotyped for the CYP3A5*3 polymorphism and for a set of insertion-deletion polymorphisms, validated as...
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