Article
Hole-in-one mutant phenotypes link EGFR/ERK signaling to epithelial tissue repair in Drosophila.
PloS one - 1 Jan 2011
Geiger Jennifer A, Carvalho Lara, Campos Isabel, Santos Ana Catarina, Jacinto Antonio
Abstract excerpt
BACKGROUND: Epithelia act as physical barriers protecting living organisms and their organs from the surrounding environment. Simple epithelial tissues have the capacity to efficiently repair wounds through a resealing mechanism. The known molecular mechanisms underlying this process appear to be conserved in both vertebrates and invertebrates, namely the involvement of the transcription factors Grainy head (Grh)...
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