Article
The grainy head transcription factor is essential for the function of the frizzled pathway in the Drosophila wing.
Mechanisms of development - 1 Jan 2004
Lee Haeryun, Adler Paul N
Abstract excerpt
The Drosophila wing is covered by an array of distally pointing hairs. This tissue planar polarity is regulated by the frizzled pathway. We have found that the function of the grainy head transcription factor is essential for the function of the frizzled pathway. grainy head mutant cells fail to localize planar polarity proteins at either the proximal or distal sides of wing cells and produce multiple hairs of...
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