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Article

ESE‐1 inhibits the invasion of oral squamous cell carcinoma in conjunction with MMP‐9 suppression

7 Jun 2007

Abstract excerpt

OBJECTIVES: Matrix metalloproteinases (MMPs) regulated by ets transcription factors facilitate carcinoma cell invasion. An ets family member, ESE-1, is expressed specifically in epithelial tissues, but its association with MMPs is obscure. In this study, we investigated whether ESE-1 regulates invasion of oral squamous cell carcinoma (SCC) via transcriptional activity of MMP-9. METHODS: HSC-3 and KB were used as...

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PMID: 18302674
DOI: 10.1111/j.1601-0825.2007.01360.x

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