TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

doi:10.1002/pros.22832

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Article

TCF7L2 type 2 diabetes risk variant, lifestyle factors, and incidence of prostate cancer.

The Prostate - 1 Sept 2014

Drake Isabel, Wallström Peter, Hindy George, Ericson Ulrika, Gullberg Bo, Bjartell Anders, Sonestedt Emily, Orho-Melander Marju, Wirfält Elisabet

Abstract excerpt

BACKGROUND: Variation in transcription factor 7-like 2 (TCF7L2), the strongest genetic risk factor for type 2 diabetes (T2D), may play a role in prostate cancer (PCa) depending on lifestyle factors. The aims of this study were to determine if TCF7L2 rs7903146 is associated with risk of PCa and if the association is modified by lifestyle factors independently of T2D status. METHODS: We prospectively followed 8,558...

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PMID: 24961829
DOI: 10.1002/pros.22832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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