Article
Associations between TCF7L2 polymorphisms and risk of breast cancer among Hispanic and non-Hispanic white women: the Breast Cancer Health Disparities Study.
Breast cancer research and treatment - 1 Nov 2012
Connor Avonne E, Baumgartner Richard N, Baumgartner Kathy B, Kerber Richard A, Pinkston Christina, John Esther M, Torres-Mejia Gabriela, Hines Lisa, Giuliano Anna, Wolff Roger K, Slattery Martha L
Abstract excerpt
The transcription factor 7-like 2 (TCF7L2) gene is part of the Wnt/β-catenin signaling pathway and plays a critical role in cell development and growth regulation. TCF7L2 variants rs12255372 and rs7903146 have been associated with risk of Type 2 diabetes. Few epidemiological studies have examined the association between TCF7L2 and breast cancer risk. We investigated the associations between 25 TCF7L2 single...
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