Article
Detection of adamantane-resistant influenza on a microarray.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 2008
Townsend Michael B, Smagala James A, Dawson Erica D, Deyde Varough, Gubareva Larisa, Klimov Alexander I, Kuchta Robert D, Rowlen Kathy L
Abstract excerpt
BACKGROUND: Influenza A has the ability to rapidly mutate and become resistant to the commonly prescribed influenza therapeutics, thereby complicating treatment decisions. OBJECTIVE: To design a cost-effective low-density microarray for use in detection of influenza resistance to the adamantanes. STUDY DESIGN: We have taken advantage of functional genomics and microarray technology to design a DNA microarray that...
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