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Article

Application of a full-genome microarray-based assay for the study of genetic variability of West Nile virus.

Journal of virological methods - 1 Aug 2012

Grinev Andriyan, Lu Zhong, Chizhikov Vladimir, Rios Maria

Abstract excerpt

Viral adaptation through fixation of spontaneous mutations is an important factor potentially associated with reoccurrence of West Nile virus (WNV) outbreaks in the New World. The emergence of new genetic variants of WNV represents an important public health issue because it may affect the sensitivity of WNV screening and diagnostic assays, as well as the development and efficacy of WNV vaccines and anti-viral...

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PMID: 22561983
DOI: 10.1016/j.jviromet.2012.04.001

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