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Article

Microarray-based assay for the detection of genetic variations of structural genes of West Nile virus.

Journal of virological methods - 1 Dec 2008

Grinev Andriyan, Daniel Sylvester, Laassri Majid, Chumakov Konstantin, Chizhikov Vladimir, Rios Maria

Abstract excerpt

Adaptation through fixation of spontaneous mutations in the viral genome is considered to be one of the important factors that enable recurrent West Nile virus (WNV) outbreaks in the U.S. Genetic variations can alter viral phenotype and virulence, and degrade the performance of diagnostic and screening assays, vaccines, and potential therapeutic agents. A microarray assay was developed and optimized for the...

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PMID: 18930080
DOI: 10.1016/j.jviromet.2008.09.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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