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Article

PMA counteracts G protein actions on CaV2.2 channels in rat sympathetic neurons.

Archives of biochemistry and biophysics - 1 May 2008

Díaz-Cárdenas Alfonso F, Arenas Isabel, García David E

Abstract excerpt

Protein kinase C (PKC)-induced phosphorylation and G protein-mediated inhibition of Ca(V)2.2 N-type Ca2+ channels counteract exerting opposing modulatory responses at the channel level. At present, the most striking question remaining is whether prominent enhancement of the Ca2+ current (I(Ca)) observed under PKC activation arises from relief of G-protein tonic inhibition. Here, by using patch-clamp methods in...

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Identifiers

PMID: 18298939
DOI: 10.1016/j.abb.2008.01.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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