Article
Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Mar 2008
Shimada Nobukazu, Shinagawa Toshie, Ishii Shunsuke
Abstract excerpt
The promyelocytic leukemia (PML) tumor suppressor protein accumulates in PML nuclear bodies (PML-NBs), and can induce growth arrest, cellular senescence and apoptosis. PML has also been localized in the cytoplasm, although its function in this localization remains elusive. A general property of p...
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