Article
Suppressed expression of LDHB promotes pancreatic cancer progression via inducing glycolytic phenotype.
Medical oncology (Northwood, London, England) - 1 May 2015
Cui Jiujie, Quan Ming, Jiang Weihua, Hu Hai, Jiao Feng, Li Ning, Jin Ziliang, Wang Lei, Wang Yu, Wang Liwei
Abstract excerpt
Lactate dehydrogenase B (LDHB) is widely expressed in adult somatic tissue and is one of the two subunits of lactate dehydrogenase, which is the key glycolytic enzyme and catalyzes the interconversion of pyruvate and lactate. However, the roles of LDHB in glycolysis and tumor progression were obs...
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