Article
Lipoprotein Lp(a) in homozygous familial hypercholesterolemia: density profile, particle heterogeneity and apolipoprotein(a) phenotype.
Atherosclerosis - 1 Jan 1991
Guo H C, Chapman M J, Bruckert E, Farriaux J P, De Gennes J L
Abstract excerpt
Homozygous familial hypercholesterolemia (FH) is a genetic disorder featuring a functional defect in cellular LDL receptors, marked elevation in circulating LDL concentrations, and premature atherosclerosis. The potential atherogenic role of apo B-containing lipoproteins other than LDL in this di...
Topics
- Adolescent
- Adult
- Apolipoprotein A-I
- Apolipoproteins
- Apolipoproteins A
- Apolipoproteins B
- Apoprotein(a)
- Centrifugation, Density Gradient
- Child
- Cholesterol
- Electrophoresis, Polyacrylamide Gel
- Female
- Homozygote
- Humans
- Hyperlipoproteinemia Type II
- Immunoblotting
- Lipids
- Lipoprotein(a)