Chimpanzee lipoprotein(A): Relationship between apolipoprotein(A) isoform size and the density profile of lipoprotein(A) in animals with different heterozygous apo(A) phenotypes.

Abstract excerpt

In a previous study [C. Doucet et al., J. Lipid Res 35:263-270, 1994], we have shown that plasma lipoprotein (a) [Lp(a)] levels were significantly elevated in a population of unrelated chimpanzees as compared to those in normolipidemic human subjects. Nonetheless, the inverse correlation between Lp(a) levels and apolipoprotein (a) [apo(a)] isoforms typical of man was maintained in the chimpanzee. In the present...

Topics

• Animals
• Apolipoproteins
• Apoprotein(a)
• Cholesterol
• Enzyme-Linked Immunosorbent Assay
• Female
• Heterozygote
• Humans
• Lipoprotein(a)
• Male
• Pan troglodytes