Article
Subclasses of low-density lipoprotein and very low-density lipoprotein in familial combined hyperlipidemia: relationship to multiple lipoprotein phenotype.
Arteriosclerosis, thrombosis, and vascular biology - 1 Apr 2004
Georgieva A M, van Greevenbroek M M J, Krauss R M, Brouwers M C G J, Vermeulen V M M-J, Robertus-Teunissen M G, van der Kallen C J H, de Bruin T W A
Abstract excerpt
OBJECTIVE: The present study addresses the presence of distinct metabolic phenotypes in familial combined hyperlipidemia (FCHL) in relation to small dense low-density lipoprotein (sd LDL) and very low-density lipoprotein (VLDL) subclasses. METHODS AND RESULTS: Hyperlipidemic FCHL relatives (n=72) were analyzed for LDL size by gradient gel electrophoresis. Pattern B LDL (sd LDL, particle size <258 A) and pattern A...
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