Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variation in lipoprotein(a) concentration associated with different apolipoprotein(a) alleles.

The Journal of clinical investigation - 1 Apr 1994

Perombelon Y F, Soutar A K, Knight B L

Abstract excerpt

Plasma lipoprotein(a) (Lp(a)) concentrations vary considerably between individuals. To examine the variation for products of the same and different apolipoprotein(a) (apo(a)) alleles, conditions were established whereby phenotyping immunoblots could be used to estimate the concentration of Lp(a) associated with the constituent apo(a) isoforms. In these studies 28 distinct isoforms were identified, each differing...

Topics

Alleles
Apolipoprotein B-100
Apolipoproteins
Apolipoproteins B
Apoprotein(a)
Humans
Hyperlipoproteinemia Type II
Lipoprotein(a)
Pedigree

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 8163653
DOI: 10.1172/JCI117126
PMCID: PMC294162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8163653-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in lipoprotein(a) concentration associated with different apolipoprotein(a) alleles.PMID 8163653Read ↗

Polymorphisms in the apolipoprotein(a) gene and their relationship to allele size and plasma lipoprotein(a) concentration.Semantic proximity Read ↗

Assessment of Apolipoprotein(a) Isoform Size Using Phenotypic and Genotypic Methods.Semantic proximity Read ↗

Impact of apo(a) length polymorphism and the control of plasma Lp(a) concentrations: evidence for a threshold effect.Semantic proximity Read ↗

[Apolipoprotein (a) isoform size determination. Value and limits of high resolution phenotyping by agarose gel electrophoresis].Semantic proximity Read ↗

Differential expression of double-band apolipoprotein(a) phenotypes in healthy Spanish subjects detected by SDS-agarose immunoblotting.Semantic proximity Read ↗

Lp(a) concentrations are related to plasma lipid concentrations.Semantic proximity Read ↗

Variation in lipoprotein(a) concentrations among individuals with the same apolipoprotein (a) isoform is determined by the rate of lipoprotein(a) production.Semantic proximity Read ↗

Differences in Lp[a] concentrations and apo[a] polymorphs between black and white Americans.Semantic proximity Read ↗

Hypervariable polymorphism of APO(a) in blacks and whites as reflected by phenotyping.Semantic proximity Read ↗

Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature.Semantic proximity Read ↗

Lipoprotein Lp(a): effects of allelic variation at the LPA locus.Semantic proximity Read ↗

Apolipoprotein (a) alleles determine lipoprotein (a) particle density and concentration in plasma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.