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Article

Neuregulin-1 haplotype HAP(ICE) is associated with lower hippocampal volumes in schizophrenic patients and in non-affected family members.

Journal of psychiatric research - 1 Nov 2008

Gruber Oliver, Falkai Peter, Schneider-Axmann Thomas, Schwab Sibylle G, Wagner Michael, Maier Wolfgang

Abstract excerpt

The neuregulin-1 (NRG1) gene on chromosome 8p has been suggested as a potential susceptibility gene for schizophrenia. The exact way in which genetic variation in NRG1 might impact on this susceptibility for the disorder is a focus of current research. The present study aimed at investigating the possible relationship between a putative NRG1 at-risk haplotype (HAP(ICE)) and hippocampal volumes in schizophrenic...

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Source

Identifiers

PMID: 18291420
DOI: 10.1016/j.jpsychires.2008.01.009

Genes

NRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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