Article
Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic/Scottish risk haplotype.
Molecular psychiatry - 1 Jul 2004
Li T, Stefansson H, Gudfinnsson E, Cai G, Liu X, Murray R M, Steinthorsdottir V, Januel D, Gudnadottir V G, Petursson H, Ingason A, Gulcher J R, Stefansson K, Collier D A
Abstract excerpt
To determine if neuregulin 1 (NRG1) is associated with schizophrenia in Asian populations, we investigated a Han Chinese population using both a family trio design and a case-control design. A total of 25 microsatellite markers and single nucleotide polymorphisms (SNPs) were genotyped spanning the 1.1 Mb NRG1 gene including markers of a seven-marker haplotype at the 5' end of the gene found to be in excess in...
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