Article
The progression of gliomas is associated with cancer stem cell phenotype.
Oncology reports - 1 Mar 2008
Kong Doo-Sik, Kim Mi Hyun, Park Woong-Yang, Suh Yeon-Lim, Lee Jung-Il, Park Kwan, Kim Jong Hyun, Nam Do-Hyun
Abstract excerpt
Since cancer stem cells in brain tumors were introduced, there have been few explanations regarding the role of cancer stem cells in the progression of glioma. Here, we investigated their major molecular changes in tumor progression in relation to the stem cell subpopulation. Using 12 surgical specimens of gliomatosis cerebri (GC) in the early and advanced stages, we measured the expression of a panel of cell...
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