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Article

Sox2: regulation of expression and contribution to brain tumors

27 May 2016

Abstract excerpt

Tumors of the CNS are composed of a complex mixture of neoplastic cells, in addition to vascular, inflammatory and stromal components. Similar to most other tumors, brain tumors contain a heterogeneous population of cells that are found at different stages of differentiation. The cancer stem cell hypothesis suggests that all tumors are composed of subpopulation of cells with stem-like properties, which are...

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PMID: 27230973
DOI: 10.2217/cns-2016-0001

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