Article
Lack of association between apolipoprotein E polymorphism and vascular dementia in Koreans.
Journal of geriatric psychiatry and neurology - 1 Mar 2008
Kim Ki Woong, Youn Jong-Chul, Han Moon-Ku, Paik Nam Jong, Lee Tae Joo, Park Joon Hyuk, Lee Seok Bum, Choo Il Han, Lee Dong Young, Jhoo Jin Hyeong, Woo Jong Inn
Abstract excerpt
To investigate an association of vascular dementia (VD) with the apolipoprotein E (APOE) polymorphism, the APOE polymorphism of 100 VD patients, 100 age- and gender-matched Alzheimer disease (AD) patients, and 200 age- and gender-matched nondemented control (NC) subjects was genotyped. The distribution of APOE polymorphism was compared. Neither the APOE epsilon4 allele nor the APOE epsilon2 allele was more...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Asian People
- Dementia, Vascular
- Female
- Genetic Predisposition to Disease
- Genotype