Article
Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Mar 2003
Choi Yoon-Ho, Kim Ji-Hae, Kim Doh Kwan, Kim Jong-Won, Kim Duk-Kyung, Lee Mee Sook, Kim Cheol Ho, Park Sang Chul
Abstract excerpt
BACKGROUND: Genetic polymorphisms of angiotensin-converting enzyme (ACE) and apolipoprotein E (APOE) have been reported to be associated with human longevity and dementia in the elderly. However, whether such putative longevity genes exert the same effects on different ethnic groups living in different environments is not well known. METHODS: We investigated the distributions of the ACE and APOE genotypes and...
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