Article
Apolipoprotein ɛ4 is Associated with Dementia and Cognitive Impairment Predominantly Due to Alzheimer's Disease and Not with Vascular Cognitive Impairment: A Singapore-Based Cohort.
Journal of Alzheimer's disease : JAD - 1 Jan 2016
Chai Yuek Ling, Yeo Hazel Kai-Hui, Wang Jiehao, Hilal Saima, Ikram Mohammad Kamran, Venketasubramanian Narayanaswamy, Wong Boon-Seng, Chen Christopher Li-Hsian
Abstract excerpt
BACKGROUND AND OBJECTIVE: While the association for apolipoprotein ɛ4 allele (APOE4) with Alzheimer's disease (AD) has been consistently confirmed, the association with vascular cognitive impairment (VCI) is unclear. We therefore explored the relationship of APOE with both AD and cerebrovascular disease (CeVD) by examining the prevalence of APOE4 in AD, AD with CeVD and vascular dementia (VaD), as well as in...
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