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Article

Attenuated vancomycin bactericidal activity against Staphylococcus aureus hemB mutants expressing the small-colony-variant phenotype.

Antimicrobial agents and chemotherapy - 1 Apr 2008

Tsuji Brian T, von Eiff Christof, Kelchlin Pamela A, Forrest Alan, Smith Patrick F

Abstract excerpt

The in vitro bactericidal activities of vancomycin against Staphylococcus aureus hemB mutants displaying the small-colony-variant phenotype and their parental strains were evaluated. Vancomycin killing activities against hemB mutants were markedly attenuated, demonstrating approximately 50% less...

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Identifiers

PMID: 18285476
DOI: 10.1128/AAC.01254-07
PMCID: PMC2292514

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18285476-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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