Article
Physiology and antibiotic susceptibility of Staphylococcus aureus small colony variants.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2002
Baumert Nicole, von Eiff Christof, Schaaff Franziska, Peters Georg, Proctor Richard A, Sahl Hans-Georg
Abstract excerpt
Small colony variants (SCV) are slow-growing subpopulations with altered metabolism and reduced antibiotic susceptibility which, in the case of Staphylococcus aureus, can cause persisting and recurrent infections. We studied four SCVs and their corresponding parent strains: one clinical strain pair, one menaquinone-deficient spontaneous mutant, and two constructed mutants obtained by inactivation of hemB in S....
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