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Article

Genomic characterization of a vancomycin-intermediate Staphylococcus aureus (VISA) small colony variant after long-term antibiotic therapy.

Journal of global antimicrobial resistance - 1 Jun 2026

Urushibara Noriko, Aung Meiji Soe, Sakurada Minoru, Kaji Kentaro, Sakai Yoshiyuki, Kobayashi Nobumichi

Abstract excerpt

OBJECTIVES: Vancomycin (VCM)-intermediate Staphylococcus aureus (VISA) and small-colony variants (SCVs) are clinically important phenotypes that are frequently difficult to treat and commonly encountered in persistent or recurrent infections. We previously reported a VISA strain, HV2019-1, isolated during a relapse episode of pacemaker-associated bloodstream infection. In the present study, we further...

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Genome, Bacterial
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Staphylococcal Infections
Staphylococcus aureus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vancomycin Resistance

Whole Genome Sequencing

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PMID: 41990876
DOI: 10.1016/j.jgar.2026.04.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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